What is ESBLs?

ESBLs (extended-spectrum beta-lactamases) are enzymes produced by certain bacteria that make them resistant to many common antibiotics, including penicillins and cephalosporins. Bacteria carrying ESBLs can cause infections, such as urinary tract or bloodstream infections, that are more challenging to treat, requiring different antibiotic choices.

Many people carry ESBL-producing bacteria in their gut without any symptoms or illness (colonisation), which is different from having an active infection. Hospitals and care facilities take specific infection control precautions to reduce the spread of ESBL-producing bacteria between patients.